Breaking the limits in glycan recognition by NMR
نویسندگان
چکیده
Breaking the limits in glycan recognition by NMR (RECGLYCANMR) is a multidisciplinary project that combines state-of-the-art chemistry and chemical biology methods, including vitro in-cell NMR, biophysics protocols under crowding conditions to ask answer pivotal questions related sugar molecular Nature are intimately infection inflammation diseases.
منابع مشابه
Breaking the Limits in Analyzing Carbohydrate Recognition by NMR Spectroscopy: Resolving Branch‐Selective Interaction of a Tetra‐Antennary N‐Glycan with Lectins
The biological recognition of complex-type N-glycans is part of many key physiological and pathological events. Despite their importance, the structural characterization of these events remains unsolved. The inherent flexibility of N-glycans hampers crystallization and the chemical equivalence of individual branches precludes their NMR characterization. By using a chemoenzymatically synthesized...
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ژورنال
عنوان ژورنال: The project repository journal
سال: 2023
ISSN: ['2632-4067']
DOI: https://doi.org/10.54050/prj1720316